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Critical Reviews in Oral Biology & Medicine
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4(2):141-158 (1993)     Crit Rev Oral Biol Med
© 1993 SAGE Publications

The Therapy of Oral Lichen Planus

Drore Eisen, D.D.S., M.D.

Dermatology Associates of Cincinnati, Inc., Mercy Health Plaza, Beechmont at Five Mile Road, 7691 Five Mile Road, Cincinnati, OH 45230

Oral lichen planus is a chronic mucocutaneous disease that is relatively common. Although many patients are asymptomatic and require no therapy, those who exhibit atrophic and erosive lesions are often a challenge to treat. All therapies are palliative, and none is effective universally. Currently employed treatment modalities include corticosteroids administered topically, intralesionally, or systemically. Alternative therapies include topical and systemic retinoids, griseofulvin, Cyclosporine, and surgery. Other medical treatments and experimental modalities, including mouth PUVA, have been reported to be effective. Controversy concerning the efficacy of all these treatments suggests that oral lichen planus is a heterogeneous disorder. Eliminating lichenoid drug eruptions, candidiasis, trauma, contact mucositis, and emotional stress may play a role in the management of these patients. This article is a review of the many treatments and measures that have been employed in the management of patients with oral lichen planus.

Key Words: oral lichen planus • corticosteroids • retinoids • Cyclosporine • griseofulvin • Dapsone. PUVA.

Critical Reviews in Oral Biology & Medicine, Vol. 4, No. 2, 141-158 (1993)
DOI: 10.1177/10454411930040020101
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