This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Kayaoglu, G. Articles by Ørstavik, D. Search for Related Content PubMed PubMed Citation Social Bookmarking                         What's this?

VIRULENCE FACTORS OF ENTEROCOCCUS FAECALIS: RELATIONSHIP TO ENDODONTIC DISEASE

¹ Gazi University, Faculty of Dentistry, Department of Endodontics and Conservative Treatment, 82. Sokak 06510 Emek, Ankara, Turkey;
² NIOM, Scandinavian Institute of Dental Materials, Haslum, Norway

View larger version (59K): [in this window] [in a new window]   Figure. An endodontic disease model related to virulence factors of E. faecalis. The virulence factors of the bacterium inside the dentinal tubules and the root canal are released to the periradicular area, where they elicit leukocyte attraction or stimulate leukocytes to produce inflammatory mediators or lytic enzymes. Some of the bacteria may translocate to the periradicular lesion as well. The injurious virulence factors and leukocyte products are shown in the zone between the interrupted lines. In a magnified window, the adhesion of the bacterium to diverse elements of the dentin is depicted. Bacterial products fighting other bacteria are also included. Note that names in black boxes are the products of the bacterium. Abbreviations: Adh, surface adhesins; AS, aggregation substance; Bact, bacteriocins; BS, binding substance; CP, collagen peptides; Cyl, cytolysin; Ef, Enterococcus faecalis; Elas, elastase; Gel, gelatinase; Hya, hyaluronidase; H2O2, hydrogen peroxide; IFN-, gamma interferon; IL, interleukin; LE, lysosomal enzymes; LTA, lipoteichoic acid; NO, nitric oxide; O2.–, superoxide anion; PGE2, prostaglandin E2; SP, sex pheromones; and TNF, tumor necrosis factor. O2.–: The dot denotes the presence of an unpaired electron, and the superscript denotes the negative charge.

Critical Reviews in Oral Biology & Medicine, Vol. 15, No. 5, 308-320 (2004)
DOI: 10.1177/154411130401500506


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?